CRC Hospital Taiping began functioning in April 2011 in a room located in the CME building. Dr Letchuman Ramanathan, Head of Medical Department and Consultant Endocrinologist, was appointed to lead the centre. Initially he was assisted by only one Research Officer. Currently, the CRC team consists of a medical officer, a research officer and a pharmacist.

In December 2011, CRC Hospital Taiping underwent upgrading works, with funding from National CRC, to occupy the whole of the east wing of the CME building. The dawn of 2012 saw a newly refurbished CRC which consists of the CRC office, a computer room, 3 trial clinics, patient waiting lounge, a procedure room, a meeting room, a server room, an investigational product storage room and a document room with controlled security access.

As part of the CRC Network of the Ministry of Health (MOH), the role of CRC Hospital Taiping is to support quality and ethical research to improve patient outcomes. CRC Taiping also coordinates and facilitates Industry-Sponsored Clinical Research conducted in Hospital Taiping.