The Clinical Research Centre Hospital Tengku Ampuan Afzan Kuantan (CRC HTAA) Pahang has been operational since November 2003 as part of the Network of Clinical Research Centres of the Ministry of Health (MOH). The objectives for the setting up of CRC HTAA include: to cultivate a research culture among clinicians, compilation of information regarding all clinical research activities carried out in HTAA, and provide assistance to researchers. In the long term, CRC HTAA aims to ensure excellence and quality of clinical trails and establishing a centre of excellence in specific clinical areas. Among services to researchers include providing guidelines on application to conduct drug related clinical trials, procedures for getting grants, coordination with other departments and role as Contract Research Organization (CRO).