The Clinical Research Centre Hospital Sultanah Aminah Johor Bharu (CRC HSAJB) is newly established in Johor as part of the Network of Clinical Research Centres of the Ministry of Health (MOH). CRC HSAJB is responsible for conducting quality and ethical research to improve patient outcome in Hospital Sultanah Aminah.

Currently located on the Fifth Floor of the main building (Bangunan Induk) of Hospital Sultanah Aminah, the CRC HSAJB is under the care of the Technical and Research Committee of Hospital Sultanah Aminah. The CRC HSAJB organizes training and professional development courses (speakers invited from CRC Hospital Kuala Lumpur) and assists in problems faced by clinicians in the conduct of their clinical research.