The Clinical Research Centre (CRC) was established in 2000 as the clinical research arm of the Ministry of Health to conduct clinical trials, clinical epidemiology and economic research, and manage complex medical databases.

Under the purview of the National Institutes of Health (NIH), the CRC promotes, supports and conducts quality and ethical research to improve patient outcome. The CRC also conducts training and professional development courses and assist in problems faced by clinicians in the conduct of their clinical research.

Initially established in Kuala Lumpur Hospital, CRC has gradually expanded into a network of 27 CRCs nationwide

1. Kuala Lumpur Hospital, Wilayah Persekutuan Kuala Lumpur (2000)
2. Raja Perempuan Bainun Hospital, Perak (2001)
3. Penang Hospital, Penang (2003)
4. Sarawak General Hospital, Sarawak (2003)
5. Tengku Ampuan Afzan Hospital, Pahang (2004)
6. Sultanah Bahiyah Hospital, Kedah (2006)
7. Selayang Hospital, Selangor (2006)
8. Tuanku Ja'afar Hospital, Negeri Sembilan (2006)
9. Melaka Hospital, Melaka (2006)
10. Sultanah Aminah Hospital, Johor (2006)
11. Sultanah Nur Zahirah Hospital, Terengganu (2006)
12. Raja Perempuan Zainab II Hospital, Kelantan (2006)
13. Queen Elizabeth Hospital, Sabah (2006)
14. Tuanku Fauziah Hospital, Perlis (2007)
15. Ampang Hospital, Kuala Lumpur (2007)
16. Serdang Hospital, Selangor (2008)
17. Tengku Ampuan Rahimah Hospital, Selangor (2008)
18. Sungai Buloh Hospital, Selangor (2010)
19. Putrajaya Hospital, Wilayah Persekutuan Putrajaya (2010)
20. Sibu Hospital, Sarawak (2010)
21. Likas Hospital, Sabah (2011)
22. Taiping Hospital, Perak (2011)
23. Seberang Jaya Hospital, Penang (2011)
24. Seri Manjung Hospital, Perak (2011)
25. Sultan Ismail Hospital, Johor (2011)
26. Queen Elizabeth II Hospital, Sabah (2011)
27. Miri Hospital (2012)

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