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Centre for Clinical Epidemiology (CCE)

About Us

The Centre for Clinical Epidemiology (CCE) at the Institute for Clinical Research (ICR) undertakes research on the prevention, aetiology, diagnosis, prognosis and treatment of disease. CCE employs a variety of research methodologies in the conduct of population-based research with potential clinical and public health applications, in line with national research priority areas. CCE also provides support in planning, designing, and conducting research in many disease areas, particularly non-communicable diseases.

The vision of CCE is to become the leading centre of patient-oriented research in providing evidence that underpin national health policies. Our mission is to contribute evidence through epidemiological research to bridge the gaps between clinical practice and health policy in the best interest of patient care.


CCE has a strong focus on studies which can provide evidence that informs decision-making of patients, healthcare providers and policymakers. Our current research areas include:

Cancer Research
During the 58th World Health Assembly in 2005, the Member States were called upon to intensify action against cancer by developing and reinforcing cancer control program through four components, namely prevention, early detection, diagnosis & treatment and palliative care. The cancer research conducted in CCE are in line with these key domains of the National Cancer Control Program to provide useful information and evidence to the key stakeholders.
Palliative Care Research
Palliative care is an approach that improves the quality of life of patients and their families facing problems associated with life-threatening illness. Many patients who were diagnosed with advanced stages of disease are likely to suffer physically and psychologically in view of limited resources for early diagnosis and treatment. To provide optimum care for this group of patients, palliative care is very important. However, this area is under researched in Malaysia. In line with the concept of Universal Health Coverage, our research aims to explore both epidemiological and clinical aspects of palliative care, to push forward the concept of “leave no one behind” within the scope of palliative care services.
Aging Research
According to published statistics, Malaysia is at risk of becoming an “ageing population”. Malaysia statistics shows that those aged 60 years and above stood at 7.9% in 2010 and projected to reach 15.3% by 2030. Every person in the world should have the opportunity to live a long and healthy life. Healthy ageing is a process of developing and maintaining the functional ability that enables wellbeing in older age. By understanding ageing as a process rather than a disease, our research aims to create environments and opportunities that enable people to be able to do what they value throughout their lives.
Dengue Research
Dengue infection has been recognized as the fastest spreading mosquito-borne viral disease by WHO. Malaysia is hyper-endemic with dengue virus and the number of cases has been escalating over the years. Our research projects focus on dengue epidemiology and its health burden, with the aim to provide evidence to guide dengue control and prevention program by MOH Malaysia.


Research Consultation Clinic
Research consultation clinic (RCC) is a free consultation service provided by experienced researchers from CCE to assist MOH investigators/researchers in their clinical research. The RCC usually entertain the following requests:
  1.1 Brainstorming
1.2 Proposal development
1.3 Research design
1.4 Data management
1.5 Interpretation and output presentation
Training and Professional Development
As an offshoot of our research activities, CCE frequently provides training especially for investigators participating in research and health professionals who have an interest in clinical research. The training courses provided by CCE are often developed and organized in collaboration with other relevant agencies such as professional societies, academic institutions, etc.

Organization Chart (CEU)


Contact for Enquiries
Email : cce.icrmalaysia@gmail.com
Tel : +603 3362 7700 / 8807
Fax : +603 3362 7701

Center for Clinical Epidemiology (CCE)
Institute for Clinical Research (ICR)
Block B4, National Institute of Health Complex (NIH)
1, Jalan Setia Murni, U13/52, Seksyen U13
40170 Shah Alam, Selangor, Malaysia

Dr. Woon Yuan Liang
Head of Centre
+603 3362 8804
ORCID: 0000-0003-4834-9175
ylwoon@crc.moh.gov.my / ylwoon.crc@gmail.com

Dr. Shamala Devi A/P Karalasingam
Senior Consultant Obstetrician and Gynaecologist
+603 3362 8801

Dr. Leong Chin Tho
Medical Officer
+603 33628809
ORCID: 0000-0002-3688-5467
leongct@crc.moh.gov.my / johnlct@gmail.com

Dr. Loo Ching Ee
Medical Officer
+603 3362 8808
ORCID: 0000-0003-4727-2890
chingee@crc.moh.gov.my / chingee.crc@gmail.com

Dr. Wong Wen Jun
Medical Officer
+603 3362 8819
ORCID: 0000-0003-2695-8033
wwjun@crc.moh.gov.my /gabrielle5018@yahoo.com

Dr. Ramani Subramaniam Kalianan
Medical Officer
+603 3362 8848
ORCID: 0000-0003-3225-282X
dr.ramani@crc.moh.gov.my / dr.skramani@gmail.com

Lim Wei Yin (Amanda)
+603 3362 8842
ORCID: 0000-0002-2612-0604
weiyinlim@crc.moh.gov.my / amanda.limwy.crc@gmail.com

Yip Yan Yee
+603 3362 8843
ORCID: 0000-0003-1900-3183
yyyip@crc.moh.gov.my / yipyanyee.crc@gmail.com

Teh Hoon Shien
+603 3362 8841
ORCID: 0000-0002-4117-5494

Hing Yee Liang (Nicholas)
+603 3362 8810
ORCID: 0000-0003-4530-8466
hingyl@crc.moh.gov.my / nickhing8855@gmail.com

Yang Su Lan
+603 3362 8812
ORCID: 0000-0002-8554-356X
slyang@moh.gov.my / yslan89@hotmail.com

Shridevi Subramaniam
Research Officer
+603 3362 8813
ORCID: 0000-0002-8392-8036

Nur Ain Athirah Mat Zaki
General Office Assistant
+603 3362 8807